Invention Grant
- Patent Title: Process for the preparation of liraglutide
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Application No.: US15523384Application Date: 2015-10-31
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Publication No.: US10344069B2Publication Date: 2019-07-09
- Inventor: Suresh Kumar Vadlamani , Patil Nilesh Dagadu , Mohammed Abdul Shafee , Sanjay Devidas Patil , Nagana Goud Agasaladinni
- Applicant: Auro Peptides Ltd , Suresh Kumar Vadlamani , Patil Nilesh Dagadu , Mohammed Abdul Shafee , Sanjay Devidas Patil , Nagana Goud Agasaladinni
- Applicant Address: IN Hyderabad
- Assignee: Auro Peptides Ltd.
- Current Assignee: Auro Peptides Ltd.
- Current Assignee Address: IN Hyderabad
- Agent Jay R Akhave
- Priority: IN5472/CHE/2014 20141031
- International Application: PCT/IB2015/058429 WO 20151031
- International Announcement: WO2016/067271 WO 20160506
- Main IPC: C07K14/605
- IPC: C07K14/605

Abstract:
The present invention relates to a process for the preparation of Liraglutide, which comprises: a) synthesis of suitable fragments (protected) by solid phase peptide synthesis; b) coupling of the suitable fragments on solid support; c) concurrently cleaving the protected peptide from the solid support and de-protecting the peptide; d) purification of Liraglutide (crude) on reverse phase HPLC; e) isolating pure Liraglutide.
Public/Granted literature
- US20180251511A1 PROCESS FOR THE PREPARATION OF LIRAGLUTIDE Public/Granted day:2018-09-06
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