公开(公告)号：US10344069B2

公开(公告)日：2019-07-09

申请号：US15523384

申请日：2015-10-31

申请人： Auro Peptides Ltd ,  Suresh Kumar Vadlamani ,  Patil Nilesh Dagadu ,  Mohammed Abdul Shafee ,  Sanjay Devidas Patil ,  Nagana Goud Agasaladinni

发明人： Suresh Kumar Vadlamani ,  Patil Nilesh Dagadu ,  Mohammed Abdul Shafee ,  Sanjay Devidas Patil ,  Nagana Goud Agasaladinni

IPC分类号： C07K14/605

摘要： The present invention relates to a process for the preparation of Liraglutide, which comprises: a) synthesis of suitable fragments (protected) by solid phase peptide synthesis; b) coupling of the suitable fragments on solid support; c) concurrently cleaving the protected peptide from the solid support and de-protecting the peptide; d) purification of Liraglutide (crude) on reverse phase HPLC; e) isolating pure Liraglutide.