A system for a differential trans-impedance amplifier circuit comprising: an amplifier having a pair of input nodes and configured to generate an amplified replica of a differential voltage on said pair of input nodes; a photodiode; a pair of DC-blocking capacitors coupling said photodiode to said pair of input nodes; at least one resistance coupled between said pair of input nodes of said amplifier; and a bias network comprising two identical photodiode biasing resistances each photodiode biasing resistance coupled in series between said photodiode and a respective DC voltage. A feedback loop for the amplifier may include source followers that are operable to level shift voltages prior to coupling capacitors that couple said photodiode to said amplifier to ensure stable bias conditions for said amplifier. The source followers may include CMOS transistors. The amplifier may be integrated in a complementary metal-oxide semiconductor (CMOS) chip, which may include a CMOS photonics chip.