Systems and methods for conducted communication are described. In one embodiment, a method for communicating with implantable medical devices may comprise sensing, by a first medical device, a noise signal delivered into a patient's body by a second medical device and delivering, by the first medical device, a cancelling signal into the patient's body. In at least some additional embodiments the method may further comprise, while delivering the cancelling signal into the patient's body, delivering a conducted communication signal into the patient's body for reception by a second medical device.