A method and system for determining whether, when, and how an unmanned agent interrupts a human is provided. The provided method and system uses a two-step multivariate analysis to (i) process a request for human interaction to determine whether to interrupt a human, and (ii) determine when and how to interrupt the human. The provided method and system interrupts the human in a manner that reflects analysis of variables such as mission criticality, whether a delay in the mission is acceptable, and the propriety of interrupting the human.