A method for measuring a reference signal for location determination in a wireless communication system, according to an embodiment of the present invention, is performed by means of a terminal. The method comprises the steps of: receiving assistant data related to neighbor cells and a reference cell for location determination; by means of the assistant data, receiving a positioning reference signal (PRS) of a cell-specific reference signal (CRS) of the reference cell or the neighbor cells and calculating a reference signal time difference (RSTD) measurement value; and reporting the measurement value to a location server, wherein the assistant data can comprise information about the number of CRS antenna ports of the reference cell and neighbor cells, CRS cyclic prefix (CP) length information, or configuration information about multicast broadcast single frequency network (MBSFN) subframes.