Invention Grant
- Patent Title: Compositions and methods for modulating T-cell mediated immune response
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Application No.: US15256152Application Date: 2016-09-02
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Publication No.: US10407484B2Publication Date: 2019-09-10
- Inventor: Yuwen Zhu , Barish H. Edil , Richard D. Schulick , Alessandro Paniccia , Michelle Koenig , Alexander C. Schulick
- Applicant: The Regents of the University of Colorado, a body corporate
- Applicant Address: US CO Denver
- Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee Address: US CO Denver
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle; Debora Plehn-Dujowich
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; C07K14/705 ; C07K16/28 ; A61K39/395 ; A61K45/06 ; C07K14/725 ; A61K47/68 ; A61K47/69

Abstract:
The present disclosure relates to compositions and methods for modulating T-cell mediated immune response in a subject in need thereof. The method includes administering to the subject an effective amount of a CD112R protein, a fusion polypeptide, a complex including CD112R and a second protein, or an anti-CD112R antibody of the present disclosure.
Public/Granted literature
- US20170240613A1 COMPOSITIONS AND METHODS FOR MODULATING T-CELL MEDIATED IMMUNE RESPONSE Public/Granted day:2017-08-24
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