Invention Grant
- Patent Title: Heterologous expression of termite cellulases in yeast
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Application No.: US16245152Application Date: 2019-01-10
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Publication No.: US10428322B2Publication Date: 2019-10-01
- Inventor: Elena E. Brevnova , Vineet Rajgarhia , Mark Mellon , Anne Warner , John McBride , Chhayal Gandhi , Erin Wiswall
- Applicant: Lallemand Hungary Liquidity Management LLC
- Applicant Address: HU Budapest
- Assignee: Lallemand Hungary Liquidity Management LLC
- Current Assignee: Lallemand Hungary Liquidity Management LLC
- Current Assignee Address: HU Budapest
- Agency: Seed IP Law Group LLP
- Main IPC: C12N15/81
- IPC: C12N15/81 ; C12N9/42 ; C12P7/10 ; C12P19/02 ; C12P19/14

Abstract:
The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.
Public/Granted literature
- US20190127714A1 HETEROLOGOUS EXPRESSION OF TERMITE CELLULASES IN YEAST Public/Granted day:2019-05-02
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