Invention Grant
- Patent Title: Microaspiration-based lung window apparatus for obtaining microscopic image of in vivo lung tissue and method for obtaining image using same
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Application No.: US15756478Application Date: 2016-08-31
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Publication No.: US10437035B2Publication Date: 2019-10-08
- Inventor: Pil Han Kim , Inwon Park , Sunghoon Kim
- Applicant: MEDICINAL BIOCONVERGENCE RESEARCH CENTER , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Gyeonggi-do KR Daejeon
- Assignee: Medicinal Bioconvergence Research Center,Korea Advanced Institute of Science and Technology
- Current Assignee: Medicinal Bioconvergence Research Center,Korea Advanced Institute of Science and Technology
- Current Assignee Address: KR Gyeonggi-do KR Daejeon
- Agency: Leason Ellis LLP
- Priority: KR10-2015-0123216 20150831
- International Application: PCT/KR2016/009720 WO 20160831
- International Announcement: WO2017/039316 WO 20170309
- Main IPC: G02B21/36
- IPC: G02B21/36 ; A61B5/00 ; A61B5/08 ; G02B21/00

Abstract:
Disclosed are a microaspiration-based lung window apparatus for obtaining a microscopic image of in vivo lung tissue and a method for using the window apparatus to obtain cell-level and molecular level microscopic images of in vivo lung tissue while maintaining physiological respiration and circulation of an animal without interference. In one embodiment, a lung window apparatus comprises an open window having the upper and lower parts open, a cover glass placed over the upper part and lung tissue coming in contact with the lower part; an aspiration tube extending from one side of the open window to an aspiration apparatus enabling the inside of the open window to be in a vacuum state; and a tilting mount placing unit extending from one side of the open window having a tilting mount to enable the cover glass and an object lens of a confocal microscope system to stay parallel to each other.
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