Invention Grant
- Patent Title: Chiral reagents for preparation of substituted phosphorodiamidate morpholino oligomers
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Application No.: US15750087Application Date: 2016-08-05
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Publication No.: US10457698B2Publication Date: 2019-10-29
- Inventor: Atsushi Endo , Robert T. Yu , Francis Fang , Hyeong Wook Choi , Mingde Shan
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd
- Current Assignee: Eisai R&D Management Co., Ltd
- Current Assignee Address: JP Tokyo
- Agency: Buchanan Ingersoll & Rooney PC
- International Application: PCT/US2016/045876 WO 20160805
- International Announcement: WO2017/024264 WO 20170209
- Main IPC: C07D413/00
- IPC: C07D413/00 ; C07F9/6561 ; C07F9/6558 ; C07H21/00 ; A61K31/7088
Abstract:
A method of preparation of stereospecific synthesis of diastereomerically pure phosphorodiamidate morpholino oligomers (PMOs) of one of the following general formulas is provided:
Public/Granted literature
- US20180222932A1 CHIRAL REAGENTS FOR PREPARATION OF HOMOGENEOUS OLIGOMERS Public/Granted day:2018-08-09
Information query
