- 专利标题： Biochemically stabilized HIV-1 env trimer vaccine
-
申请号： US16385438申请日： 2019-04-16
-
公开(公告)号： US10463729B2公开(公告)日： 2019-11-05
- 发明人: Stephen C. Harrison , Bing Chen , Dan H. Barouch , Joseph P. Nkolola , Michael Scott Seaman
- 申请人： Beth Israel Deaconess Medical Center, Inc. , Children's Medical Center Corporation
- 申请人地址： US MA Boston US MA Boston
- 专利权人： Beth Israel Deaconess Medical Center, Inc.,Children's Medical Center Corporation
- 当前专利权人： Beth Israel Deaconess Medical Center, Inc.,Children's Medical Center Corporation
- 当前专利权人地址： US MA Boston US MA Boston
- 代理机构： Panitch Schwarze Belisario & Nadel LLP
- 主分类号： A61K39/21
- IPC分类号： A61K39/21 ; C07K14/005 ; A61K39/00 ; A61K39/12 ; C12N7/00
摘要：
Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.
公开/授权文献
- US20190240319A1 BIOCHEMICALLY STABILIZED HIV-1 ENV TRIMER VACCINE 公开/授权日：2019-08-08
信息查询
