Invention Grant
- Patent Title: In vivo stealth nanoparticle
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Application No.: US15532951Application Date: 2015-12-04
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Publication No.: US10471011B2Publication Date: 2019-11-12
- Inventor: Toshifumi Takeuchi , Yukiya Kitayama
- Applicant: Toshifumi Takeuchi , Yukiya Kitayama , System Instruments Co., Ltd.
- Applicant Address: JP Kobe-shi, Hyogo JP Kobe-shi, Hyogo JP Hachioji-shi, Tokyo
- Assignee: Toshifumi Takeuchi,Yukiya Kitayama,System Instruments Co., Ltd.
- Current Assignee: Toshifumi Takeuchi,Yukiya Kitayama,System Instruments Co., Ltd.
- Current Assignee Address: JP Kobe-shi, Hyogo JP Kobe-shi, Hyogo JP Hachioji-shi, Tokyo
- Agency: Knobbe Martens Olson & Bear, LLP
- Priority: JP2014-247252 20141205
- International Application: PCT/JP2015/006041 WO 20151204
- International Announcement: WO2016/088384 WO 20160609
- Main IPC: A61K9/14
- IPC: A61K9/14 ; C08F2/44 ; A61K47/69 ; A61K31/704 ; C08F220/56 ; A61P35/00 ; B82Y5/00 ; A61K9/00

Abstract:
Provided is a molecular imprint polymer that is capable of acquiring stealth properties through a new mechanism. The molecular imprint polymer according to the present invention, which has a plasma protein recognition sites molecularly imprinted by a plasma protein thereon and contains a constituent derived from a biocompatible monomer, is an in vivo stealth nanoparticle to be used in intravascular delivery. As the plasma protein, albumin is preferred. When carrying a drug thereon, the in vivo stealth nanoparticle according to the present invention is usable as a drug for drug delivery system.
Public/Granted literature
- US20170319485A1 IN VIVO STEALTH NANOPARTICLE Public/Granted day:2017-11-09
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