- Patent Title: Bile acid derivatives as FXR agonists and methods of use thereof
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Application No.: US15896400Application Date: 2018-02-14
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Publication No.: US10472386B2Publication Date: 2019-11-12
- Inventor: Guoqiang Wang , Yat Sun Or , Ruichao Shen , Xuechao Xing , Jiang Long , Peng Dai , Brett Granger , Jing He
- Applicant: Enanta Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore
- Main IPC: C07J41/00
- IPC: C07J41/00 ; C07J9/00 ; C07J43/00 ; C07J51/00

Abstract:
The present invention provides compounds represented by Formula I, or pharmaceutically acceptable salts, prodrugs and esters thereof, The invention also provides pharmaceutical compositions comprising these compounds and methods of using this compounds for treating FXR-mediated or TGR5-mediated diseases or conditions.
Public/Granted literature
- US20180237471A1 BILE ACID DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF Public/Granted day:2018-08-23
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