Invention Grant
- Patent Title: Antibodies specific to pyroglutamated Aβ
-
Application No.: US15288476Application Date: 2016-10-07
-
Publication No.: US10472414B2Publication Date: 2019-11-12
- Inventor: Søren Christensen , Lone Helboe
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DK201100275 20110408
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; A61K39/395 ; A61K39/40 ; C07K16/18 ; A61K39/00 ; G01N33/68 ; C07K1/00
Abstract:
The present invention relates to antibodies specific for pyroglutamated Aβ, as well as their use in the treatment of Alzheimer's disease and as use in diagnostic methods or as diagnostic imaging ligands. Further, is provided pyroglutamated N-terminal fragments of murine or human Aβ to generate antibodies and for use in therapeutic purposes.
Public/Granted literature
- US20170022268A1 Antibodies Specific to Pyroglutamated Abeta Public/Granted day:2017-01-26
Information query
