A system may include a power supply configurable to generate any of a plurality of output voltages on a power supply output node. The system also may include a voltage auto-detection power distribution (PD) controller coupled to the power supply. The voltage auto-detection PD controller is configured to monitor an input signal for detection of presence of a device coupled to the system via a cable and assert combinations of a plurality of control signals. For each combination of control signals, the voltage auto-detection PD controller measures a value of an output voltage from the power supply, stores the measured value, and generates a plurality of packets for transmission to the device. Each packet contains a parameter indicative of a measured output voltage.