A gain adjustment unit calculates a total sum of analog gains on a way from photoelectric conversion output of an image pickup device to input of an analog/digital conversion circuit with use of picked-up images provided from the analog/digital conversion circuit, the analog/digital conversion circuit being configured to convert an output of an analog processing section into a digital signal, the analog processing section being configured to transmit and amplify an image pickup signal from the image pickup device, the image pickup device being provided at an insertion portion of an endoscope, and determines, as an adjustment gain, a difference between a target value of a total sum of gains and the total sum of the analog gains, and output information.