- 专利标题： Metabolomics in pneumonia and sepsis
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申请号： US14409755申请日： 2013-06-25
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公开(公告)号： US10533989B2公开(公告)日： 2020-01-14
- 发明人: John A. Kellum , Christopher W. Seymour
- 申请人： University of Pittsburgh—Of the Commonwealth System of Higher Education
- 申请人地址： US PA Pittsburgh
- 专利权人： University Of Pittsburgh—Of The Commonwealth System Of Higher Education
- 当前专利权人： University Of Pittsburgh—Of The Commonwealth System Of Higher Education
- 当前专利权人地址： US PA Pittsburgh
- 代理机构： Medlen & Carroll, LLP
- 国际申请： PCT/US2013/047662 WO 20130625
- 国际公布： WO2014/004539 WO 20140103
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; G01N33/68 ; G01N33/52 ; G01N33/49
摘要：
The present invention describes a global metabolomic profile of patients with community acquired pneumonia (CAP) and sepsis. The metabolomic profile of endogenous small molecules blood was determined using mass-spectrometry. The global metabolomic profile in plasma demonstrated broad differences between CAP and sepsis patients when comparing those who do and do not survive at 90 days. Increases in specific metabolite biomarkers displayed on a heat map provide early diagnosis of these medical conditions to allow for early intervention and aggressive treatment.
公开/授权文献
- US20150153331A1 METABOLOMICS IN PNEUMONIA AND SEPSIS 公开/授权日：2015-06-04
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