Invention Grant
- Patent Title: On-array ligation assembly
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Application No.: US15782648Application Date: 2017-10-12
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Publication No.: US10538796B2Publication Date: 2020-01-21
- Inventor: Nicholas M Sampas , Jeffrey R Sampson
- Applicant: Agilent Technologies, Inc.
- Applicant Address: US CA Santa Clara
- Assignee: AGILENT TECHNOLOGIES, INC.
- Current Assignee: AGILENT TECHNOLOGIES, INC.
- Current Assignee Address: US CA Santa Clara
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C12N15/10 ; C12N15/66

Abstract:
Provided herein, among other things, is a method for producing a ligation product on a support. In some embodiments, the method may comprise hybridizing a first double-stranded oligonucleotides and a second double-stranded oligonucleotide to a substrate comprising surface-tethered oligonucleotides and ligating the distal ends of the first and second double-stranded oligonucleotides together, thereby producing a first ligation product that is tethered to the support at both ends.
Public/Granted literature
- US20180105853A1 ON-ARRAY LIGATION ASSEMBLY Public/Granted day:2018-04-19
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