- 专利标题: Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
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申请号: US16098260申请日: 2017-05-04
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公开(公告)号: US10544099B2公开(公告)日: 2020-01-28
- 发明人: Emily Charlotte Cherney , Liping Zhang , David K. Williams , James Aaron Balog
- 申请人: BRISTOL-MYERS SQUIBB COMPANY
- 申请人地址: US NJ Princeton
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: US NJ Princeton
- 代理机构: BakerHostetler
- 国际申请: PCT/US2017/031040 WO 20170504
- 国际公布: WO2017/192840 WO 20171109
- 主分类号: C07D215/18
- IPC分类号: C07D215/18 ; C07D215/233 ; C07D401/04 ; A61P35/00 ; A61K31/47 ; A61K31/4709 ; A61K45/06
摘要:
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
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