- Patent Title: Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
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Application No.: US16098260Application Date: 2017-05-04
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Publication No.: US10544099B2Publication Date: 2020-01-28
- Inventor: Emily Charlotte Cherney , Liping Zhang , David K. Williams , James Aaron Balog
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: BakerHostetler
- International Application: PCT/US2017/031040 WO 20170504
- International Announcement: WO2017/192840 WO 20171109
- Main IPC: C07D215/18
- IPC: C07D215/18 ; C07D215/233 ; C07D401/04 ; A61P35/00 ; A61K31/47 ; A61K31/4709 ; A61K45/06
Abstract:
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
Public/Granted literature
- US20190119216A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE Public/Granted day:2019-04-25
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