Invention Grant
- Patent Title: Bacterium constitutively producing monophosphoryl lipid A and method of producing monophosphoryl lipid A by using bacterium
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Application No.: US16026796Application Date: 2018-07-03
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Publication No.: US10557156B2Publication Date: 2020-02-11
- Inventor: Hak Suk Chung , Yu Hyun Ji , Jin Su An , Ick Chan Kwon , Eun Gyeong Yang
- Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Seoul
- Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Seoul
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: KR10-2017-0085406 20170705
- Main IPC: C12P19/12
- IPC: C12P19/12 ; C12N9/16 ; C12N9/14 ; C12P7/64
Abstract:
A bacterium that constitutively produces monophosphoryl lipid A (MLA) and a method of producing MLA by using the bacterium may simply produce MLA and a derivative thereof without acid hydrolysis, reduce a probability of natural mutation, and increase yields of MLA and a derivative thereof by constitutive expression of the MLA and derivative thereof.
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