A route inspection system includes one or more processors configured to identify a reference location in sensor data provided by one or more sensors onboard a vehicle system. The reference location is identified along a route being traveled by the vehicle system. The one or more processors also are configured to identify a location of interest in subsequent sensor data provided by the one or more sensors. The location of interest identified along the route being traveled by the vehicle system. The one or more processors also are configured to determine a degree of curvature in the route based on a difference between the reference location and the location of interest.