Invention Grant
- Patent Title: Methods for making and using sinoatrial node-like pacemaker cardiomyocytes and ventricular-like cardiomyocytes
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Application No.: US15550572Application Date: 2016-02-17
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Publication No.: US10561687B2Publication Date: 2020-02-18
- Inventor: Gordon Keller , Stephanie Protze
- Applicant: UNIVERSITY HEALTH NETWORK
- Applicant Address: CA Toronto, Ontario
- Assignee: UNIVERSITY HEALTH NETWORK
- Current Assignee: UNIVERSITY HEALTH NETWORK
- Current Assignee Address: CA Toronto, Ontario
- Agency: Proskauer Rose LLP
- International Application: PCT/CA2016/050142 WO 20160217
- International Announcement: WO2016/131137 WO 20160825
- Main IPC: C12N5/00
- IPC: C12N5/00 ; A61K35/34 ; C12N5/077 ; C12N5/10
Abstract:
Provided are methods for producing compositions comprising a population of cardiomyocytes enriched for or substantially devoid of sinoatrial node-like pacemaker cardiomyocytes (SANLCM) from human pluripotent stem cells (hPSCs), and methods of use thereof.
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