Invention Grant
- Patent Title: N-alkyl-2-phenoxyethanamines, their preparation and use
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Application No.: US15944334Application Date: 2018-04-03
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Publication No.: US10570148B2Publication Date: 2020-02-25
- Inventor: Konstantin Petrukhin , Christopher Cioffi , Graham Johnson , Nicoleta Dobri , Emily Freeman , Ping Chen , Michael Conlon , Lei Zhu
- Applicant: The Trustees of Columbia University In the City of New York
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Cooper & Dunham LLP
- Agent John P. White; Gary J. Gershik
- Main IPC: C07D498/04
- IPC: C07D498/04 ; C07D213/80 ; C07D231/56 ; C07D237/24 ; C07D239/28 ; C07D249/04 ; C07D471/04 ; C07D487/04 ; C07D491/052 ; C07C233/56 ; C07D213/79

Abstract:
The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is alkyl; A is absent or present, and when present is —C(O)— or —C(O)NH—; B is substituted or unsubstituted monocycle, bicycle, heteromonocycle, heterobicycle, benzyl, CO2H or (C1-C4 alkyl)-CO2H, wherein when B is CO2H, then A is present and is —C(O)—, or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20180222919A1 N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE Public/Granted day:2018-08-09
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