Invention Grant
- Patent Title: Muteins of clotting factor VIII
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Application No.: US14638760Application Date: 2015-03-04
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Publication No.: US10570189B2Publication Date: 2020-02-25
- Inventor: James Apgar , Debra Pittman , Mark Stahl , Laura Lin , Justin Cohen
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: PFIZER INC.
- Current Assignee: PFIZER INC.
- Current Assignee Address: US NY New York
- Main IPC: C07K14/755
- IPC: C07K14/755 ; A61K38/00 ; A61K47/61 ; A61K38/37

Abstract:
The present disclosure provides muteins of FVIII to which a biocompatible polymer may be attached to increase the circulatory half-life of the muteins, as well as conjugates of such muteins and biocompatible polymers.
Public/Granted literature
- US20150306234A1 MUTEINS OF CLOTTING FACTOR Vlll Public/Granted day:2015-10-29
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