Invention Grant
- Patent Title: Process for producing magnetic monodisperse polymer particles
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Application No.: US15170251Application Date: 2016-06-01
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Publication No.: US10573443B2Publication Date: 2020-02-25
- Inventor: Christoph Seidel , Jens Christian Bolle , Sandra Recklies
- Applicant: Roche Diagnostics Operations, Inc.
- Applicant Address: US IN Indianapolis
- Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee: Roche Diagnostics Operations, Inc.
- Current Assignee Address: US IN Indianapolis
- Agency: Roche Diagnostics Operations, Inc.
- Priority: EP13195723 20131204
- Main IPC: H01F1/44
- IPC: H01F1/44 ; C08F257/00 ; C08K9/10

Abstract:
Disclosed is a simplified process for producing magnetic polymer particles. The process comprises: (a) providing a composition having a liquid monomer which is radical polymerizable, a radical initiator soluble in the monomer, a steric stabilizer, and a ferrofluid comprising surfactant-coated colloidal magnetic particles in a carrier fluid which is miscible with the monomer; (b) preparing an emulsion from a polar solvent which is immiscible with the monomer, and the composition of step (a); (c) adding seed polymer particles to the emulsion, mixing to form a seeded emulsion, and incubating the seeded emulsion, thereby swelling the seed polymer particles; and (d) activating the radical initiator and polymerizing the monomer in the swollen seed polymer particles; thereby producing the magnetic polymer particles. The process forms monodisperse magnetic particles. The particles are characterized by a uniform distribution of magnetic material, and an absence of magnetite bleeding.
Public/Granted literature
- US20160276080A1 PROCESS FOR PRODUCING MAGNETIC MONODISPERSE POLYMER PARTICLES Public/Granted day:2016-09-22
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