Invention Grant
- Patent Title: Bicyclic dihydropyrimidine-carboxamide derivatives as Rho-Kinase inhibitors
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Application No.: US15850720Application Date: 2017-12-21
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Publication No.: US10584128B2Publication Date: 2020-03-10
- Inventor: Alessandro Accetta , Fabio Rancati , Anna Maria Capelli , David Edward Clark , Patrizia Tisselli , Christine Edwards , Gurdip Bhalay
- Applicant: CHIESI FARMACEUTICI S.p.A.
- Applicant Address: IT Parma
- Assignee: CHIESI FARMACEUTICI S.p.A.
- Current Assignee: CHIESI FARMACEUTICI S.p.A.
- Current Assignee Address: IT Parma
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: EP16205661 20161221
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D487/04 ; A61P11/06 ; A61K9/00 ; A61K45/06 ; A61P11/00 ; A61P37/00
Abstract:
Bicyclic dihydropyrimidine-carboxamide compounds of formula I described herein inhibit Rho Kinase and may be useful in the treatment of many disorders associated with ROCK enzymes mechanisms, such as pulmonary diseases including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), and pulmonary arterial hypertension (PAH).
Public/Granted literature
- US20180170939A1 BICYCLIC DIHYDROPYRIMIDINE-CARBOXAMIDE DERIVATIVES AS RHO- KINASE INHIBITORS Public/Granted day:2018-06-21
Information query
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