Invention Grant
- Patent Title: Process for preparation of sulfonylurea bile acid derivatives
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Application No.: US15826233Application Date: 2017-11-29
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Publication No.: US10584145B2Publication Date: 2020-03-10
- Inventor: Guoqiang Wang , Yong He , Peng Dai , Guoyou Xu , Bin Wang , Jiang Long , Yat Sun Or
- Applicant: Enanta Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore
- Main IPC: C07J41/00
- IPC: C07J41/00 ; C07J51/00 ; C07J9/00
Abstract:
The present invention relates to processes for preparing a compound of Formula I: or a pharmaceutically acceptable salt or solvate thereof. These compounds and pharmaceutical compositions are useful as FXR or TGR5 modulators. Specifically, the present invention relates to bile acid derivatives and methods for their preparation and use. The present invention relates to a process for the preparation of a compound (II) and its salts and derivatives which are useful intermediates in the synthesis of biologically active molecules, especially in the synthesis of FXR and TGR5 modulators. The present invention also relates to a process for the preparation of a compound (III) and its diethylamine salt.
Public/Granted literature
- US20180148469A1 PROCESS FOR PREPARATION OF SULFONYLUREA BILE ACID DERIVATIVES Public/Granted day:2018-05-31
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