Invention Grant
- Patent Title: Methods and organisms with increased carbon flux efficiencies
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Application No.: US15108259Application Date: 2014-12-23
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Publication No.: US10597684B2Publication Date: 2020-03-24
- Inventor: Anthony P. Burgard , Robin E. Osterhout , Stephen J. Van Dien , Priti Pharkya , Tae Hoon Yang , Jungik Choi
- Applicant: Genomatica, Inc.
- Applicant Address: US CA San Diego
- Assignee: Genomatica, Inc.
- Current Assignee: Genomatica, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Jones Day
- International Application: PCT/US2014/072178 WO 20141223
- International Announcement: WO2015/100338 WO 20150702
- Main IPC: C12P7/18
- IPC: C12P7/18 ; C12P7/42 ; C07K14/245 ; C12N9/00 ; C12N1/20 ; C12N9/88 ; C12N9/52 ; C12N15/52 ; C12N9/16 ; C12N9/02 ; C12N9/12
Abstract:
The invention is directed to a non-naturally occurring microbial organism comprising a first attenuation of a succinyl-CoA synthetase or transferase and at least a second attenuation of a succinyl-CoA converting enzyme or a gene encoding a succinate producing enzyme within a multi-step pathway having a net conversion of succinyl-CoA to succinate.
Public/Granted literature
- US20160326553A1 METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES Public/Granted day:2016-11-10
Information query
