- 专利标题： Antibodies and immunocytokines
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申请号： US15480525申请日： 2017-04-06
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公开(公告)号： US10604576B2公开(公告)日： 2020-03-31
- 发明人: Jamie Campbell , Nikole Sandy Nee Waddell , Stephen D. Gillies , Volker Germaschewski , Cassandra van Krinks , Ian Kirby , Miha Kosmac , Steve Arkinstall , Thomas Gallagher
- 申请人： Kymab Limited
- 申请人地址： GB
- 专利权人： Kymab Limited
- 当前专利权人： Kymab Limited
- 当前专利权人地址： GB
- 代理机构： Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/395 ; C07K14/55 ; C07K16/46 ; C07K19/00 ; A61K39/00
摘要：
The present invention relates to anti-PD-L1 antibodies, bispecific antibodies containing one domain with specificity to PD-L1, and to immunocytokines comprising an anti-PD-L1 antibody fused to a cytokine, such as IL-2. The present invention also provides methods of treatment, uses and pharmaceutical compositions comprising the antibodies, bispecific antibodies and immunocytokines.
公开/授权文献
- US20170362321A1 ANTIBODIES AND IMMUNOCYTOKINES 公开/授权日：2017-12-21