- 专利标题: Polypeptide having endonuclease activity and method for producing the same
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申请号: US16146564申请日: 2018-09-28
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公开(公告)号: US10655112B2公开(公告)日: 2020-05-19
- 发明人: Tozo Nishiyama
- 申请人: KANEKA CORPORATION
- 申请人地址: JP Osaka
- 专利权人: KANEKA CORPORATION
- 当前专利权人: KANEKA CORPORATION
- 当前专利权人地址: JP Osaka
- 代理机构: Osha Liang LLP
- 优先权: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@4fdf993c
- 主分类号: C12N9/44
- IPC分类号: C12N9/44 ; C12N9/24 ; C12N9/16 ; C12N15/09 ; C12N1/16 ; C12P21/02 ; C12N15/52 ; C12N15/81 ; C07H21/04
摘要:
A polypeptide includes an amino acid sequence selected from the group consisting of: an amino acid sequence having at least 85% sequence identity to the amino acid sequence of SEQ ID NO: 1; and an amino acid sequence derived from the amino acid sequence of SEQ ID NO: 1 by substitution, deletion, and/or addition of one or more amino acid residues. A yeast host expressing the polypeptide in a secretory production system does not add an N-linked sugar chain to the polypeptide, and the polypeptide has endonuclease activity.
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