Invention Grant
- Patent Title: Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof
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Application No.: US16025324Application Date: 2018-07-02
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Publication No.: US10676467B2Publication Date: 2020-06-09
- Inventor: Zhude Tu , Adam Rosenberg , Hui Liu , Junbin Han
- Applicant: Zhude Tu , Adam Rosenberg , Hui Liu , Junbin Han
- Applicant Address: US MO St. Louis
- Assignee: Washington University
- Current Assignee: Washington University
- Current Assignee Address: US MO St. Louis
- Agency: Stinson LLP
- Main IPC: C07D413/04
- IPC: C07D413/04 ; C07D419/04 ; C07D413/10 ; C07D271/06 ; C07B59/00 ; C07D413/12
Abstract:
Among the various aspects of the present disclosure is the provision of a compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof. Provided are imaging agents for imaging S1P1 and S1P1 associated diseases, disorders, and conditions. Also provided are therapeutic compositions and methods for the treatment of S1P1 associated diseases, disorders, and conditions.
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