• 专利标题: Targeted gas-filled microvesicles formulation
  • 申请号: US15536393
    申请日: 2015-12-17
  • 公开(公告)号: US10682429B2
    公开(公告)日: 2020-06-16
  • 发明人: Philippe BussatAnne Lassus
  • 申请人: BRACCO SUISSE S.A.
  • 申请人地址: CH Manno
  • 专利权人: BRACCO SUISSE S.A.
  • 当前专利权人: BRACCO SUISSE S.A.
  • 当前专利权人地址: CH Manno
  • 代理机构: Vivicar Law, PLLC
  • 优先权: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@41cafbb4
  • 国际申请: PCT/EP2015/080199 WO 20151217
  • 国际公布: WO2016/097130 WO 20160623
  • 主分类号: A61K49/22
  • IPC分类号: A61K49/22 A61B8/08
Targeted gas-filled microvesicles formulation
摘要:
Suspension of gas-filled microvesicles comprising a targeting ligand for binding to KDR or VEGF/KDR complex. The suspension is obtained by reconstituting a freeze-dried residue with a carbohydrate-containing solution in the presence of a physiologically acceptable gas and is stabilized by the presence of histidine.
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