Invention Grant
- Patent Title: Triazole pyridyl compounds as agonists of the APJ receptor
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Application No.: US16347970Application Date: 2017-11-03
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Publication No.: US10689367B2Publication Date: 2020-06-23
- Inventor: Yinhong Chen , Alan C. Cheng , Mikkel V. Debenedetto , Paul John Dransfield , James S. Harvey , Jonathan Houze , Aarif Yusuf Khakoo , Su-Jen Lai , Zhihua Ma , Vatee Pattaropong , Gayathri Swaminath , Charles Kreiman , David C. Moebius , Ankit Sharma
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Bernard P. Friedrichsen
- International Application: PCT/US2017/059839 WO 20171103
- International Announcement: WO2018/093580 WO 20180524
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D405/14 ; C07D413/14 ; A61P9/04 ; C07D417/14 ; A61K45/06 ; C07D401/12
Abstract:
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the structures where the definitions of the variables are provided herein.
Public/Granted literature
- US20190300507A1 TRIAZOLE PYRIDYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR Public/Granted day:2019-10-03
Information query
