Invention Grant
- Patent Title: Anti-GITR antibodies for cancer diagnostics
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Application No.: US15578874Application Date: 2016-06-02
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Publication No.: US10690674B2Publication Date: 2020-06-23
- Inventor: Xi-Tao Wang , Olufemi A. Adelakun , Anne C. Lewin , Alan J. Korman , Mark J. Selby , Changyu Wang , Haichun Huang , Karla A. Henning , Nils Lonberg , Mohan Srinivasan , Michelle Minhua Han , Guodong Chen , Richard Y. Huang , Indrani Chakraborty , Susan Chien-Szu Wong , Huiming Li
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- International Application: PCT/US2016/035514 WO 20160602
- International Announcement: WO2016/196792 WO 20161208
- Main IPC: G01N33/566
- IPC: G01N33/566 ; G01N33/574 ; C07K16/28

Abstract:
Provided herein are diagnostic antibodies that bind to glucocorticoid-induced tumor necrosis factor receptor (GITR). Such antibodies are useful for methods of detecting the expression of GITR in biological samples, for example, tumor tissue, and identifying a cancer patient likely to respond to anti-GITR immunotherapy or predicting whether a cancer patient will respond to anti-GITR immunotherapy.
Public/Granted literature
- US20180164321A1 ANTI-GITR ANTIBODIES FOR CANCER DIAGNOSTICS Public/Granted day:2018-06-14
Information query
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