Methods, systems, and apparatus for audio noise reduction from a drone are disclosed. An example apparatus includes an acoustic sensor to gather acoustic data and at least one rotational motion sensor to gather rotational motion data of a first rotor and second rotational motion data of a second rotor. The example apparatus also includes an analyzer to identify a first filter that matches the first rotational motion data and identify a second filter that matches the second rotational motion data. The analyzer also is to filter the acoustic data into filtered acoustic data with the first identified filter and the second identified filter and generate an audio signal based on the filtered acoustic data.