Invention Grant
- Patent Title: Sulfonyl pyridyl TRP inhibitors
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Application No.: US16269973Application Date: 2019-02-07
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Publication No.: US10695348B2Publication Date: 2020-06-30
- Inventor: Vishal Verma , Matthew Volgraf , Baihua Hu
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Robert C. Hall
- Main IPC: C07D401/02
- IPC: C07D401/02 ; C07D401/12 ; C07D401/14 ; C07D515/04 ; A61K31/506 ; C07D491/048 ; A61P11/00

Abstract:
The invention provides compounds of formula I: and pharmaceutically acceptable salts thereof where R1 is a substituted or unsubstituted phenyl or a fused bicyclic comprising a substituted or unsubstituted phenyl. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.
Public/Granted literature
- US20190167681A1 SULFONYL PYRIDYL TRP INHIBITORS Public/Granted day:2019-06-06
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