![Substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-A]pyridine-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-C][1,2,4]triazol-3-ones, and use thereof](/docs/US/2020-07-28/US10722501B2/abs.jpg.600x600.jpg)
- 专利标题： Substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-A]pyridine-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-C][1,2,4]triazol-3-ones, and use thereof
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申请号： US16300480申请日： 2017-05-08
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公开(公告)号： US10722501B2公开(公告)日： 2020-07-28
- 发明人: Nicole Biber , Damian Brockschnieder , Kersten Matthias Gericke , Florian Kölling , Klemens Lustig , Jörg Meding , Heinrich Meier , Thomas Neubauer , Martina Schäfer , Andreas Timmermann , Dmitry Zubov , Carsten Terjung , Niels Lindner , Volker Badock , Dieter Moosmayer , Hideki Miyatake Ondozabal , Stephen Moore , Alexander Schulz
- 申请人： BAYER AKTIENGESELLSCHAFT , BAYER PHARMA AKTIENGESELLSCHAFT
- 申请人地址： DE Leverkusen DE Berlin
- 专利权人： BAYER AKTIENGESELLSCHAFT,BAYER PHARMA AKTIENGESELLSCHAFT
- 当前专利权人： BAYER AKTIENGESELLSCHAFT,BAYER PHARMA AKTIENGESELLSCHAFT
- 当前专利权人地址： DE Leverkusen DE Berlin
- 代理机构： Morrison & Foerster LLP
- 优先权： com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@6593f5dc
- 国际申请： PCT/EP2017/060900 WO 20170508
- 国际公布： WO2017/194459 WO 20171116
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; A61K31/506 ; C07D471/04 ; A61K31/4375 ; A61K31/4709 ; A61K31/497 ; C07D519/00 ; A61K45/06 ; A61K31/444 ; A61P11/00 ; A61P29/00
![Substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-A]pyridine-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-C][1,2,4]triazol-3-ones, and use thereof](/abs-image/US/2020/07/28/US10722501B2/abs.jpg.150x150.jpg)
摘要：
The present application relates to novel substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo[2,1-c][1,2,4]triazol-3-ones of formula (I), to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of lung inflammation disorders.
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