The invention relates to medicine, namely to cardiac surgery.The object of the invention is to raise the effectiveness of implantation of the HeartMate III left ventricular assist device by minimizing postoperative complications and improving the long-term results of device operation.The HeartMate III left ventricular assist device is implanted in compliance with the phased nature of the procedure. The site of implantation of the outflow cannula is carefully selected.The proposed method of implantation of the HeartMate III left ventricular assist device makes it possible to minimize the surgical causes of device thrombosis and bleeding, to avoid kinking of the outflow graft, to reduce the percentage of development of infection complications of the cable exit region, and thus to improve the long-term results of device operation.