Invention Grant
- Patent Title: Anti-glypican 3 antibody and pharmaceutical composition containing the same
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Application No.: US15771527Application Date: 2016-10-27
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Publication No.: US10752697B2Publication Date: 2020-08-25
- Inventor: Jae Chan Park , Kisu Kim , Mijung Lee , Eun-Hee Lee , Dong-Sik Kim , Eun Jung Song , Sujeong Kim , Hyung-Kwon Lim , Kyuhyun Lee , Jongwha Won , Soongyu Choi , Young Seoub Park
- Applicant: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
- Applicant Address: KR Gyeonggi-Do
- Assignee: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
- Current Assignee: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
- Current Assignee Address: KR Gyeonggi-Do
- Agency: Cantor Colburn LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@78dcc767
- International Application: PCT/KR2016/012193 WO 20161027
- International Announcement: WO2017/074074 WO 20170504
- Main IPC: C07K16/30
- IPC: C07K16/30 ; A61K47/68
Abstract:
The present invention relates to an antibody specifically binding to glypican 3 (GPC3), a nucleic acid encoding the antibody, a vector and a host cell containing the nucleic acid, a method of preparing the antibody, and a pharmaceutical composition for treating cancer or tumor, containing the antibody as an active ingredient. The antibody specifically binding to glypican 3 according to the present invention may be effectively used to treat cancer or tumor, particularly, hepatocellular carcinoma due to high affinity and specificity to glypican 3.
Public/Granted literature
- US20180346592A1 NOVEL ANTI-GLYPICAN 3 ANTIBODY AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Public/Granted day:2018-12-06
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