Invention Grant
- Patent Title: Stabilized amorphous calcium carbonate for treatment of neurological, muscular and infertility diseases or conditions
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Application No.: US16069762Application Date: 2017-01-17
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Publication No.: US10758566B2Publication Date: 2020-09-01
- Inventor: Yosef Ben , Abraham Shahar , Amir Arav
- Applicant: AMORPHICAL LTD.
- Applicant Address: IL Ness Ziona
- Assignee: AMORPHICAL LTD.
- Current Assignee: AMORPHICAL LTD.
- Current Assignee Address: IL Ness Ziona
- Agency: Dorsey & Whitney LLP
- International Application: PCT/IL2017/050059 WO 20170117
- International Announcement: WO2017/125918 WO 20170727
- Main IPC: A61K33/10
- IPC: A61K33/10 ; A61K9/00 ; A61K9/06 ; A61K9/10 ; A61P21/00 ; A61P15/08 ; A61K47/02 ; A61K47/12 ; A61K47/24 ; A61K47/26 ; C12N5/073 ; C12N5/076 ; C12N5/071

Abstract:
Stabilized amorphous calcium carbonate (ACC) for treatment of several neurological, muscular and infertility diseases and conditions is provided. In particular, the stabilized ACC may be used in the treatment of axonal defects and muscular dystrophy. In addition, provided are improved methods used in assistant reproductive technology. Examples of such methods are in vitro fertilization and improvement of sperm quality. The improved IVF method, for example, comprises addition of the stabilized ACC to the cell culture medium in which the stages of fertilization and embryo development occurs.
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