Invention Grant
- Patent Title: Means and methods for influencing the stability of cells
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Application No.: US16114483Application Date: 2018-08-28
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Publication No.: US10774308B2Publication Date: 2020-09-15
- Inventor: Hergen Spits
- Applicant: ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM , AIMM THERAPEUTICS B.V.
- Applicant Address: NL Amsterdam NL Amsterdam, Zuidoost
- Assignee: ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM,AIMM THERAPEUTICS B.V.
- Current Assignee: ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM,AIMM THERAPEUTICS B.V.
- Current Assignee Address: NL Amsterdam NL Amsterdam, Zuidoost
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Gianna J. Arnold
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K16/00 ; C12N5/18 ; C12N5/0781
Abstract:
The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines.
Public/Granted literature
- US20180371410A1 MEANS AND METHODS FOR INFLUENCING THE STABILITY OF CELLS Public/Granted day:2018-12-27
Information query
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