- 专利标题： Mucosal adjuvants and delivery systems
-
申请号： US16379535申请日： 2019-04-09
-
公开(公告)号： US10780162B2公开(公告)日： 2020-09-22
- 发明人: Billy M. Hargis , Neil R. Pumford , Marion Morgan , Srichaitanya Shivaramaiah , Guillermo Tellez-Isaias , Amanda Wolfenden
- 申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
- 申请人地址： US AR Little Rock
- 专利权人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
- 当前专利权人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
- 当前专利权人地址： US AR Little Rock
- 代理机构： Quarles & Brady LLP
- 主分类号： A61K39/39
- IPC分类号： A61K39/39 ; A61K39/112 ; A61K39/08 ; A61K39/02 ; A61K31/722 ; A61K39/12 ; A61K39/155 ; A61K39/00 ; A61K31/7004 ; C08B37/08 ; C08L5/08 ; A61K39/145
摘要：
Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject.
公开/授权文献
- US20190231869A1 NOVEL MUCOSAL ADJUVANTS AND DELIVERY SYSTEMS 公开/授权日：2019-08-01
信息查询
