- 专利标题： Use of peptides that block metadherin-SND1 interaction as treatment for cancer
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申请号： US16406837申请日： 2019-05-08
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公开(公告)号： US10786545B2公开(公告)日： 2020-09-29
- 发明人: Yibin Kang , Yongna Xing , Liling Wan , Feng Guo
- 申请人： The Trustees of Princeton University , Wisconsin Alumni Research Foundation
- 申请人地址： US NJ Princeton US WI Madison
- 专利权人： The Trustees of Princeton University,Wisconsin Alumni Research Foundation
- 当前专利权人： The Trustees of Princeton University,Wisconsin Alumni Research Foundation
- 当前专利权人地址： US NJ Princeton US WI Madison
- 代理机构： Marshall, Gerstein & Borun LLP
- 主分类号： C07K14/82
- IPC分类号： C07K14/82 ; A61K38/17 ; A61K38/08 ; C07K14/47 ; A61K38/10 ; A61P35/00
摘要：
The present disclosure related in general to methods of treating cancer by interfering with the interaction of metadherin with Staphylococcal nuclease domain-containing 1 (SND1) using peptides or other compounds that inhibit the binding of SND1 with metadherin and inhibit the activity of the MTDH-SND1 complex in tumor cells.
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