Invention Grant
- Patent Title: Patterned flow-cells useful for nucleic acid analysis
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Application No.: US14304556Application Date: 2014-06-13
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Publication No.: US10787698B2Publication Date: 2020-09-29
- Inventor: Shengrong Lin , Yir-Shyuan Wu , Kevin Gunderson , John A. Moon
- Applicant: ILLUMINA, INC.
- Applicant Address: US CA San Diego
- Assignee: ILLUMINA, INC.
- Current Assignee: ILLUMINA, INC.
- Current Assignee Address: US CA San Diego
- Agency: Illumina, Inc.
- Main IPC: C12Q1/6806
- IPC: C12Q1/6806 ; C12Q1/6837 ; G01N27/447

Abstract:
Provided is a surface having metal regions and an interstitial region having a composition that differs from the metal regions, wherein a continuous gel layer coats the surface across the metal regions and the interstitial regions. Nucleic acids or other analytes can be attached to the continuous gel layer such that a greater amount is attached over the metal regions than over the interstitial region. Also provided are methods for making such surfaces. Methods are also provided for making an array of nucleic acids or other analytes using such surfaces.
Public/Granted literature
- US20140329723A1 PATTERNED FLOW-CELLS USEFUL FOR NUCLEIC ACID ANALYSIS Public/Granted day:2014-11-06
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