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公开(公告)号：US20170197193A1
公开(公告)日：2017-07-13
申请号：US15470577
申请日：2017-03-27
Applicant: Illumina, Inc.
Inventor： M. Shane Bowen , Kevin L. Gunderson , Shengrong Lin , Maria Candelaria Rogert Bacigalupo , Kandswamy Vijayan , Yir-Shyuan Wu , Bala Murali Venkatesan , James Tsay , John M. Beierle , Lorenzo Berti , Sang Ryul Park
CPC classification number: C12Q1/6844 , B01J19/0046 , B01J2219/00529 , B01J2219/00608 , B01J2219/00621 , B01J2219/00637 , B01J2219/00641 , B01J2219/00644 , B01J2219/00648 , B01J2219/00653 , B01J2219/00659 , B01J2219/00662 , B01J2219/00722 , B01J2219/00788 , C12Q1/686 , C40B50/18 , C12Q2527/125 , C12Q2535/122 , C12Q2565/543
Abstract: A microarray is designed capture one or more molecules of interest at each of a plurality of sites on a substrate. The sites comprise base pads, such as polymer base pads, that promote the attachment of the molecules at the sites. The microarray may be made by one or more patterning techniques to create a layout of base pads in a desired pattern. Further, the microarrays may include features to encourage clonality at the sites.
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公开(公告)号：US20140200158A1
公开(公告)日：2014-07-17
申请号：US14194143
申请日：2014-02-28
Applicant: Illumina, Inc.
Inventor： M. Shane Bowen , Kevin L. Gunderson , Shengrong Lin , Maria Candelaria Rogert Bacigalupo , Kandaswamy Vijayan , Yir-Shyuan Wu , Bala Murali Venkatesan , James Tsay , John M. Beierle , Lorenzo Berti , Sang Ryul Park
IPC: C12Q1/68
CPC classification number: C12Q1/6844 , B01J19/0046 , B01J2219/00529 , B01J2219/00608 , B01J2219/00621 , B01J2219/00637 , B01J2219/00641 , B01J2219/00644 , B01J2219/00648 , B01J2219/00653 , B01J2219/00659 , B01J2219/00662 , B01J2219/00722 , B01J2219/00788 , C12Q1/686 , C40B50/18 , C12Q2527/125 , C12Q2535/122 , C12Q2565/543
Abstract: A microarray is designed capture one or more molecules of interest at each of a plurality of sites on a substrate. The sites comprise base pads, such as polymer base pads, that promote the attachment of the molecules at the sites. The microarray may be made by one or more patterning techniques to create a layout of base pads in a desired pattern. Further, the microarrays may include features to encourage clonality at the sites.
Abstract translation: 设计的微阵列在基底上的多个位点的每一个处捕获一个或多个感兴趣的分子。 这些部位包括促进分子在部位附着的基底垫，例如聚合物基底垫。 微阵列可以通过一种或多种图案化技术制成，以产生所需图案中的基底布局。 此外，微阵列可以包括在站点鼓励克隆性的特征。
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公开(公告)号：US20210108258A1
公开(公告)日：2021-04-15
申请号：US17113180
申请日：2020-12-07
Applicant: ILLUMINA, INC.
Inventor： M. Shane Bowen , Kevin L. Gunderson , Shengrong Lin , Maria Candelaria Rogert Bacigalupo , Kandaswamy Vijayan , Yir-Shyuan Wu , Bala Murali Venkatesan , James Tsay , John M. Beierle , Lorenzo Berti , Sang Ryul Park
IPC: C12Q1/6844 , C40B50/18 , C12Q1/686 , B01J19/00
Abstract: A method includes forming a patterned substrate including a plurality of base pads, using a nano-imprint lithography process. A capture substance is attached to each of the plurality of base pads, optionally through a linker, the capture substance being adapted to promote capture of a target molecule.
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公开(公告)号：US20180291444A1
公开(公告)日：2018-10-11
申请号：US15935897
申请日：2018-03-26
Applicant: ILLUMINA, INC.
Inventor： Hongxia Xu , Alex Aravanis , Shengrong Lin
IPC: C12Q1/6874 , C12Q1/6837 , C12N15/10
Abstract: The present disclosure relates to the field of molecular biology and more specifically to methods for capturing, amplifying and sequencing target polynucleotides on a solid surface.
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公开(公告)号：US11060135B2
公开(公告)日：2021-07-13
申请号：US16118268
申请日：2018-08-30
Applicant: ILLUMINA, INC.
Inventor： M. Shane Bowen , Kevin L. Gunderson , Shengrong Lin , Maria Candelaria Rogert Bacigalupo , Kandaswamy Vijayan , Yir-Shyuan Wu , Bala Murali Venkatesan , James Tsay , John M. Beierle , Lorenzo Berti , Sang Ryul Park
IPC: C12Q1/6844 , C40B50/18 , C12Q1/686 , B01J19/00 , C40B40/06
Abstract: A method includes forming a patterned substrate including a plurality of base pads, using a nano-imprint lithography process. A capture substance is attached to each of the plurality of base pads, optionally through a linker, the capture substance being adapted to promote capture of a target molecule.
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Patent Agency Ranking
公开(公告)号：US20130116153A1
公开(公告)日：2013-05-09
申请号：US13661524
申请日：2012-10-26
Applicant: ILLUMINA, INC.
Inventor： M. Shane Bowen , Kevin L. Gunderson , Shengrong Lin , Maria Candelaria Rogert Bacigalupo , Kandaswamy Vijayan , Yir-Shyuan Wu , Bala Murali Venkatesan , James Tsay , John M. Beierle , Lorenzo Berti , Sang Ryul Park
IPC: B01J19/00
CPC classification number: C12Q1/6844 , B01J19/0046 , B01J2219/00529 , B01J2219/00608 , B01J2219/00621 , B01J2219/00637 , B01J2219/00641 , B01J2219/00644 , B01J2219/00648 , B01J2219/00653 , B01J2219/00659 , B01J2219/00662 , B01J2219/00722 , B01J2219/00788 , C12Q1/686 , C40B50/18 , C12Q2527/125 , C12Q2535/122 , C12Q2565/543
Abstract: A microarray is designed capture one or more molecules of interest at each of a plurality of sites on a substrate. The sites comprise base pads, such as polymer base pads, that promote the attachment of the molecules at the sites. The microarray may be made by one or more patterning techniques to create a layout of base pads in a desired pattern. Further, the microarrays may include features to encourage clonality at the sites.
Abstract translation: 设计的微阵列在基底上的多个位点的每一个处捕获一个或多个感兴趣的分子。 这些部位包括促进分子在部位附着的基底垫，例如聚合物基底垫。 微阵列可以通过一种或多种图案化技术制成，以产生所需图案中的基底布局。 此外，微阵列可以包括在站点鼓励克隆性的特征。
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公开(公告)号：US12163180B2
公开(公告)日：2024-12-10
申请号：US17010675
申请日：2020-09-02
Applicant: ILLUMINA, INC.
Inventor： Shengrong Lin , Yir-Shyuan Wu , Kevin Gunderson , John A. Moon
IPC: C12Q1/6806 , C12Q1/6837 , G01N27/447
Abstract: Provided is a surface having metal regions and an interstitial region having a composition that differs from the metal regions, wherein a continuous gel layer coats the surface across the metal regions and the interstitial regions. Nucleic acids or other analytes can be attached to the continuous gel layer such that a greater amount is attached over the metal regions than over the interstitial region. Also provided are methods for making such surfaces. Methods are also provided for making an array of nucleic acids or other analytes using such surfaces.
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公开(公告)号：US20240117418A1
公开(公告)日：2024-04-11
申请号：US18507470
申请日：2023-11-13
Applicant: ILLUMINA, INC.
Inventor： M. Shane Bowen , Kevin L. Gunderson , Shengrong Lin , Maria Candelaria Rogert Bacigalupo , Kandaswamy Vijayan , Yir-Shyuan Wu , Bala Murali Venkatesan , James Tsay , John M. Beierle , Lorenzo Berti , Sang Ryul Park
IPC: C12Q1/6844 , B01J19/00 , C12Q1/686 , C40B50/18
CPC classification number: C12Q1/6844 , B01J19/0046 , C12Q1/686 , C40B50/18 , C40B40/06
Abstract: A microarray is designed to capture one or more molecules of interest at each of a plurality of sites on a substrate. The sites comprise base pads, such as polymer base pads, that promote the attachment of the molecules at the sites. The microarray may be made by one or more patterning techniques to create a layout of base pads in a desired pattern. Further, the microarrays may include features to encourage clonality at the sites.
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公开(公告)号：US11834704B2
公开(公告)日：2023-12-05
申请号：US17113180
申请日：2020-12-07
Applicant: ILLUMINA, INC.
Inventor： M. Shane Bowen , Kevin L. Gunderson , Shengrong Lin , Maria Candelaria Rogert Bacigalupo , Kandaswamy Vijayan , Yir-Shyuan Wu , Bala Murali Venkatesan , James Tsay , John M. Beierle , Lorenzo Berti , Sang Ryul Park
IPC: C12Q1/6844 , C40B50/18 , C12Q1/686 , B01J19/00 , C40B40/06
CPC classification number: C12Q1/6844 , B01J19/0046 , C12Q1/686 , C40B50/18 , B01J2219/00529 , B01J2219/00608 , B01J2219/00621 , B01J2219/00637 , B01J2219/00641 , B01J2219/00644 , B01J2219/00648 , B01J2219/00653 , B01J2219/00659 , B01J2219/00662 , B01J2219/00722 , B01J2219/00788 , C40B40/06 , C12Q1/686 , C12Q2527/125 , C12Q2535/122 , C12Q2565/543
Abstract: A method includes forming a patterned substrate including a plurality of base pads, using a nano-imprint lithography process. A capture substance is attached to each of the plurality of base pads, optionally through a linker, the capture substance being adapted to promote capture of a target molecule.
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公开(公告)号：US10787698B2
公开(公告)日：2020-09-29
申请号：US14304556
申请日：2014-06-13
Applicant: ILLUMINA, INC.
Inventor： Shengrong Lin , Yir-Shyuan Wu , Kevin Gunderson , John A. Moon
IPC: C12Q1/6806 , C12Q1/6837 , G01N27/447
Abstract: Provided is a surface having metal regions and an interstitial region having a composition that differs from the metal regions, wherein a continuous gel layer coats the surface across the metal regions and the interstitial regions. Nucleic acids or other analytes can be attached to the continuous gel layer such that a greater amount is attached over the metal regions than over the interstitial region. Also provided are methods for making such surfaces. Methods are also provided for making an array of nucleic acids or other analytes using such surfaces.
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