Invention Grant
- Patent Title: Hetroarylamine compounds for modulating the hedgehog pathway and preparing method and uses thereof
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Application No.: US16462589Application Date: 2017-11-22
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Publication No.: US10793542B2Publication Date: 2020-10-06
- Inventor: Mann-Yan Kuo , Ying-Shuan Lee , Yann-Yu Lu , Chia-Wei Liu , Seline Hsieh , Ju-Ying Yang
- Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
- Applicant Address: TW Taipei
- Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
- Current Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
- Current Assignee Address: TW Taipei
- Agency: Ladas & Parry LLP
- International Application: PCT/US2017/062974 WO 20171122
- International Announcement: WO2018/098250 WO 20180531
- Main IPC: C07D213/74
- IPC: C07D213/74 ; C07D239/47 ; C07D239/48 ; C07D401/04 ; C07D401/12 ; C07D403/04 ; A61P35/00 ; C07D239/38 ; C07D403/12 ; C07D413/12 ; C07D413/14 ; A61K45/06
Abstract:
The present invention provides a compound of formula (1): wherein X, Y, Z1, Z2, R1, R2, A, B, p and q are as disclosed in the specification. A pharmaceutical composition and a method for modulating the Hedgehog pathway are also provided. The present invention rurthe r provides a process for preparing the compound.
Public/Granted literature
- US20200079753A1 HETROARYLAMINE COMPOUNDS FOR MODULATING THE HEDGEHOG PATHWAY AND PREPARING METHOD AND USES THEREOF Public/Granted day:2020-03-12
Information query
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