- 专利标题： Human islet amyloid polypeptide (hIAPP) specific antibodies and uses thereof
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申请号： US16058630申请日： 2018-08-08
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公开(公告)号： US10882902B2公开(公告)日： 2021-01-05
- 发明人: Jan Grimm , Fabrice Heitz , Feng Chen , Ioana Combaluzier
- 申请人： Neurimmune Holding AG
- 申请人地址： CH Schlieren
- 专利权人： Neurimmune Holding AG
- 当前专利权人： Neurimmune Holding AG
- 当前专利权人地址： CH Schlieren
- 代理机构： Clark & Elbing LLP
- 代理商 Susan M. Michaud
- 优先权： EP12184134 20120912
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; A61K47/68 ; G01N33/577 ; G01N33/68 ; C07K14/47 ; C07K7/06 ; G01N33/543 ; A61K39/00
摘要：
Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.
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