- 专利标题: Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers
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申请号: US16900417申请日: 2020-06-12
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公开(公告)号: US10888585B2公开(公告)日: 2021-01-12
- 发明人: Heiko Schuster , Franziska Hoffgaard , Jens Fritsche , Oliver Schoor , Toni Weinschenk , Daniel Johannes Kowalewski , Chih-Chiang Tsou
- 申请人: Immatics Biotechnologies GmbH
- 申请人地址: DE Tuebingen
- 专利权人: Immatics Biotechnologies GmbH
- 当前专利权人: Immatics Biotechnologies GmbH
- 当前专利权人地址: DE Tuebingen
- 代理机构: Mcbee Moore & Vanik IP, LLC
- 优先权: DE102018103944 20180221,DE102018107224 20180327
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K35/17 ; A61K39/39 ; C07K16/28 ; C07K7/06 ; C07K14/54 ; A61P35/02 ; A61K45/06 ; C12N5/0783 ; A61K39/12 ; C07K16/24 ; A61K39/395 ; A61K38/08 ; C07K14/47 ; A61P35/00 ; A61K45/00
摘要:
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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