Invention Grant
- Patent Title: Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors
-
Application No.: US16712951Application Date: 2019-12-12
-
Publication No.: US10889567B2Publication Date: 2021-01-12
- Inventor: Jian Lin , Anna Ericsson , Ann-Marie Campbell , Gary Gustafson , Zhongguo Wang , R. Bruce Diebold , Susan Ashwell , David R. Lancia, Jr. , Justin Andrew Caravella , Wei Lu
- Applicant: FORMA Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: FORMA Therapeutics, Inc.
- Current Assignee: FORMA Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Choate, Hall & Stewart, LLP
- Agent John P. Rearick; Erica M. D'Amato
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; C07D471/04 ; A61P35/00 ; A61K31/47
Abstract:
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: where A, U, W1, W2, W3, R1-R6, and R9 are described herein.
Public/Granted literature
- US20200223822A1 PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS Public/Granted day:2020-07-16
Information query
