Invention Grant
- Patent Title: Method for producing diphenylmethane derivative
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Application No.: US16557180Application Date: 2019-08-30
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Publication No.: US10889574B2Publication Date: 2021-01-12
- Inventor: Hee-kyoon Yoon , Se-Hwan Park , Ji-sung Yoon , Soongyu Choi , Hee Jeong Seo , Eun-Jung Park , Younggyu Kong , Kwang-Seop Song , Min Ju Kim , So Ok Park
- Applicant: DAEWOONG PHARMACEUTICAL CO., LTD. , GREEN CROSS CORPORATION
- Applicant Address: KR Gyeonggi-do; KR Gyeonggi-do
- Assignee: DAEWOONG PHARMACEUTICAL CO., LTD.,GREEN CROSS CORPORATION
- Current Assignee: DAEWOONG PHARMACEUTICAL CO., LTD.,GREEN CROSS CORPORATION
- Current Assignee Address: KR Gyeonggi-do; KR Gyeonggi-do
- Agency: Sughrue Mion, PLLC
- Priority: KR10-2016-0075910 20160617
- Main IPC: C07D409/04
- IPC: C07D409/04 ; C07D407/04 ; C07D307/78 ; B01D9/00 ; C07B51/00

Abstract:
The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing.
Public/Granted literature
- US20190382390A1 METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE Public/Granted day:2019-12-19
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